This multistep protocol for diagnosing PID starts from the clinical presentation of the patient, which can be recognized by all doctors. Its multi-stage design allows timely identification of potential PID using specific warning signs and simple screening tests in the initial phases of the protocol.
Although many PIDs present in childhood, the most common clinically significant PID, common variable immunodeficiency (CVID), may present at any age. Therefore, the protocol is aimed for both paediatric and adult patients.
You can choose between downloading the pdf containing the tables and protocols from the publication and using the interactive webapplication based on the tables and protocols from the publication which will guide you through the various steps. Explanatory text can be found in the original publication and its references.